5-LOX INHIBITOR WITH APRESFLEX 100MG 60 VEGETARIAN Life Extension

5-lipoxygenase (5-LOX) is a member of the lipoxy-genase family of enzymes. It transforms fatty acids into leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been linked to common degenerative effects in aging individuals.9-13

Normal aging results in higher-than-desired levels of 5-LOX.

The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohy­drates, trigger overproduction of arachidonic acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme.

5-LOX breaks down arachidonic acid to pro-inflam­matory compounds like leukotriene B4,14 a molecule that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself facilitates undesirable cell division changes. 15,16

The good news is that an extract of the Indian plant Boswellia serrata has been shown to neutralize 5-LOX. Used for centuries to help with inflammatory issues, boswellia acts as a natural 5-LOX inhibitor, intervening at the cellular level to block its unwanted effects. Confirmatory data reveal that a compound contained in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid)17,18 is the key to its beneficial action.

The problem is that boswellia is poorly absorbed into the blood.19 For this reason, a patent-pending, standardized form of boswellia called AprèsFlex® is being introduced. AprèsFlex® absorbs into the blood 52% more than previously available boswellia extracts.19

Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.

*It should be noted that although Life Extension®’s previous 5-LOXIN® formulation contained at least a 30% concentration of AKBA, the new AprèsFlex® formula delivers more AKBA into the bloodstream, offering greater efficacy at a 20% concentration. One capsule of 5-LOX Inhibitor with AprèsFlex® supplies the same amount of AprèsFlex® as four vegetarian capsules of the new ArthroMax™ with Theaflavins & AprèsFlex®.